After discontinuation of Seroquel for a week I cannot sleep with 100mg. I went up to 200mg but no much help (side effects). I also tried 400mg but got terrible heart problems. What should I do? Should I decrease or increase dosing of Seroquel?

ADDITION:
My (bad quality) doctor say I should try to use 400mg but I think she isn't making right decision.

Sorry to hear about your difficulties with Seroquel. When taking psychiatric medication it is important to take it consistently, as going on and off or forgetting to take your dose can certainly be tough on your body and cause side effects.

From what I understand individuals 13 years or older can take up to 800mg or Seroquel with relative safety, so the dose your doctor is recommending is within the norm. Obviously if you are having heart problems from the medication (2 to 10 percent of people on Seroquel suffer from rapid heart rate AKA tachycardia) you should tell your doctor immediately so you can determine whether or not to alter your dose or change your medication. That is something you can only determine in person and with a psychiatrist however. If you feel your doctor is not right for you then you should definitely seek a second opinion. Your treatment is in your hands, so it is important to find a doctor you like and feel you can trust.

Seroquel is a fairly strong drug used for Bipolar and Schizophrenia. Both of these disorders can be quite debilitating and drug use is generally required to keep them in check. The medications for these disorders can have strong side effects but that almost always beats the alternative.

Best of luck,
Dr. Williams

NEVER ... self-prescribe your medications ...